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primary antibodies against hfap  (R&D Systems)


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    R&D Systems primary antibodies against hfap
    Primary Antibodies Against Hfap, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary antibodies against hfap/product/R&D Systems
    Average 94 stars, based on 5 article reviews
    primary antibodies against hfap - by Bioz Stars, 2026-04
    94/100 stars

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    a , Representative longitudinal PET/CT and CT images of unilateral bleomycin (BLM)-induced pulmonary fibrosis in <t>hFAP-knock-in</t> (hFAP-BLM) mice imaged with 18 F-FAPI and in wild-type C57BL/6-BLM mice imaged with 68 Ga-NOTA-1A12 at days 3, 7, 14, 21, and 28 after modeling. White dashed lines delineate the fibrotic lung regions. b , Quantitative analysis of probe uptake in fibrotic lung regions expressed as SUV mean. Data are presented as mean ± SD ( n = 8∼10 per group). Statistical significance was determined using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, ns: not significant. c , Schematic diagram of the sequential dual-probe PET/CT imaging protocol in the bleomycin-induced pulmonary fibrosis crab-eating macaque model. The macaque was first imaged with 18 F-FAPI on day 4 post-BLM instillation, followed by 68 Ga-NOTA-1A12 imaging on day 6 after sufficient radioactive decay. d , Representative axial, coronal, and maximum intensity projection (MIP) PET/CT images showing lung fibrotic regions with probe accumulation.
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    a , Representative longitudinal PET/CT and CT images of unilateral bleomycin (BLM)-induced pulmonary fibrosis in <t>hFAP-knock-in</t> (hFAP-BLM) mice imaged with 18 F-FAPI and in wild-type C57BL/6-BLM mice imaged with 68 Ga-NOTA-1A12 at days 3, 7, 14, 21, and 28 after modeling. White dashed lines delineate the fibrotic lung regions. b , Quantitative analysis of probe uptake in fibrotic lung regions expressed as SUV mean. Data are presented as mean ± SD ( n = 8∼10 per group). Statistical significance was determined using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, ns: not significant. c , Schematic diagram of the sequential dual-probe PET/CT imaging protocol in the bleomycin-induced pulmonary fibrosis crab-eating macaque model. The macaque was first imaged with 18 F-FAPI on day 4 post-BLM instillation, followed by 68 Ga-NOTA-1A12 imaging on day 6 after sufficient radioactive decay. d , Representative axial, coronal, and maximum intensity projection (MIP) PET/CT images showing lung fibrotic regions with probe accumulation.
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    hfap antibody  (R&D Systems)
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    Irradiation (IR) promoted FAP + KF proliferation and inhibited senescence, accompanied by high energy production. In vitro , primary KFs with or without IR treatment were analyzed by <t>anti-hFAP</t> and anti-hVimentin <t>antibody</t> <t>staining</t> (A) . Representative images of SA-β-gal staining (B) ; senescent cells are stained green, scale bar = 100 μm. The percentage of senescent cells in FAP- versus FAP + KFs at 72 h after IR (C) . Data are representative of three independent samples and are presented as the mean ± SD; n = 6; ****, p < 0.001. IR promoted FAP + KF proliferation (D) and increased intracellular ATP production (E) . Data from three experiments with essentially the same results were combined and are presented as the mean ± SD; n = 3; *, p < 0.05; **, p < 0.01; ****, p < 0.001.
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    Irradiation (IR) promoted FAP + KF proliferation and inhibited senescence, accompanied by high energy production. In vitro , primary KFs with or without IR treatment were analyzed by <t>anti-hFAP</t> and anti-hVimentin <t>antibody</t> <t>staining</t> (A) . Representative images of SA-β-gal staining (B) ; senescent cells are stained green, scale bar = 100 μm. The percentage of senescent cells in FAP- versus FAP + KFs at 72 h after IR (C) . Data are representative of three independent samples and are presented as the mean ± SD; n = 6; ****, p < 0.001. IR promoted FAP + KF proliferation (D) and increased intracellular ATP production (E) . Data from three experiments with essentially the same results were combined and are presented as the mean ± SD; n = 3; *, p < 0.05; **, p < 0.01; ****, p < 0.001.
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    Image Search Results


    a , Representative longitudinal PET/CT and CT images of unilateral bleomycin (BLM)-induced pulmonary fibrosis in hFAP-knock-in (hFAP-BLM) mice imaged with 18 F-FAPI and in wild-type C57BL/6-BLM mice imaged with 68 Ga-NOTA-1A12 at days 3, 7, 14, 21, and 28 after modeling. White dashed lines delineate the fibrotic lung regions. b , Quantitative analysis of probe uptake in fibrotic lung regions expressed as SUV mean. Data are presented as mean ± SD ( n = 8∼10 per group). Statistical significance was determined using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, ns: not significant. c , Schematic diagram of the sequential dual-probe PET/CT imaging protocol in the bleomycin-induced pulmonary fibrosis crab-eating macaque model. The macaque was first imaged with 18 F-FAPI on day 4 post-BLM instillation, followed by 68 Ga-NOTA-1A12 imaging on day 6 after sufficient radioactive decay. d , Representative axial, coronal, and maximum intensity projection (MIP) PET/CT images showing lung fibrotic regions with probe accumulation.

    Journal: medRxiv

    Article Title: A DDR2-targeted PET tracer images activated fibroblasts in early pulmonary fibrosis

    doi: 10.1101/2025.11.26.25341068

    Figure Lengend Snippet: a , Representative longitudinal PET/CT and CT images of unilateral bleomycin (BLM)-induced pulmonary fibrosis in hFAP-knock-in (hFAP-BLM) mice imaged with 18 F-FAPI and in wild-type C57BL/6-BLM mice imaged with 68 Ga-NOTA-1A12 at days 3, 7, 14, 21, and 28 after modeling. White dashed lines delineate the fibrotic lung regions. b , Quantitative analysis of probe uptake in fibrotic lung regions expressed as SUV mean. Data are presented as mean ± SD ( n = 8∼10 per group). Statistical significance was determined using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, ns: not significant. c , Schematic diagram of the sequential dual-probe PET/CT imaging protocol in the bleomycin-induced pulmonary fibrosis crab-eating macaque model. The macaque was first imaged with 18 F-FAPI on day 4 post-BLM instillation, followed by 68 Ga-NOTA-1A12 imaging on day 6 after sufficient radioactive decay. d , Representative axial, coronal, and maximum intensity projection (MIP) PET/CT images showing lung fibrotic regions with probe accumulation.

    Article Snippet: To generate stable overexpression models, lentiviral vectors carrying human DDR2 or hFAP complementary DNA (IGE Biotechnology, Guangzhou, China) were constructed and co-transfected with packaging plasmids psPAX2 and pMD2.G into 293T cells using Lipofectamine 3000 (Invitrogen).

    Techniques: Positron Emission Tomography-Computed Tomography, Knock-In, Imaging

    Irradiation (IR) promoted FAP + KF proliferation and inhibited senescence, accompanied by high energy production. In vitro , primary KFs with or without IR treatment were analyzed by anti-hFAP and anti-hVimentin antibody staining (A) . Representative images of SA-β-gal staining (B) ; senescent cells are stained green, scale bar = 100 μm. The percentage of senescent cells in FAP- versus FAP + KFs at 72 h after IR (C) . Data are representative of three independent samples and are presented as the mean ± SD; n = 6; ****, p < 0.001. IR promoted FAP + KF proliferation (D) and increased intracellular ATP production (E) . Data from three experiments with essentially the same results were combined and are presented as the mean ± SD; n = 3; *, p < 0.05; **, p < 0.01; ****, p < 0.001.

    Journal: Frontiers in Cell and Developmental Biology

    Article Title: Radiation-induced FAP + fibroblasts are involved in keloid recurrence after radiotherapy

    doi: 10.3389/fcell.2022.957363

    Figure Lengend Snippet: Irradiation (IR) promoted FAP + KF proliferation and inhibited senescence, accompanied by high energy production. In vitro , primary KFs with or without IR treatment were analyzed by anti-hFAP and anti-hVimentin antibody staining (A) . Representative images of SA-β-gal staining (B) ; senescent cells are stained green, scale bar = 100 μm. The percentage of senescent cells in FAP- versus FAP + KFs at 72 h after IR (C) . Data are representative of three independent samples and are presented as the mean ± SD; n = 6; ****, p < 0.001. IR promoted FAP + KF proliferation (D) and increased intracellular ATP production (E) . Data from three experiments with essentially the same results were combined and are presented as the mean ± SD; n = 3; *, p < 0.05; **, p < 0.01; ****, p < 0.001.

    Article Snippet: The cells were analyzed by staining with an AF488-conjugated anti hFAP antibody (R&D Systems, FAB3715G-100) and a PE-conjugated anti-hVimentin antibody (BD, 562337).

    Techniques: Irradiation, In Vitro, Staining